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1999-2000 General Catalog
University of California, Riverside
BIOMEDICAL SCIENCES
Subject abbreviation: BMSC
Faculty | Program
Undergraduate Curricula | Graduate Curricula Undergraduate Courses | Graduate Courses | Professional Courses Michael B. Stemerman, M.D., Divisional Dean and Program Director
Professors
Associate Professors
Assistant Professor
** Adjunct Associate Professor
Clinical Professors
Associate Clinical Professors
Assistant Clinical Professors
Steering Committee
UCR/UCLA PROGRAM IN BIOMEDICAL SCIENCES The Biomedical Sciences Program is an innovative approach to medical education developed by the University of California, Riverside, the UCLA School of Medicine and the clinically affiliated medical centers in the surrounding communities of Riverside. It offers highly qualified students the opportunity to earn the M.D. degree in seven years instead of eight. It emphasizes the education of physicians who deal with the entire spectrum of disease diagnosis and treatment. Moreover, it provides a social and cultural background for its participants by including electives in the humanities and in the social and behavioral sciences as part of the curriculum. The Biomedical Sciences Program admits freshmen qualified for entrance into the University of California. Admission is granted to high school graduates entering UCR in the fall quarter. In addition, high school applicants to the UCR/UCLA Program in Biomedical Sciences must have demonstrated a high level of scholarship in high school so as to provide a strong foundation for undertaking the rigorous, accelerated, first-year curriculum. Admission is also subject to the following criteria: 1. At least three high school laboratory courses (e.g., biology, chemistry, physics) 2. Mathematics competency so as to qualify for college level calculus 3. English composition proficiency so as to qualify for placement either in ENGL 001A or BSWT 001 at the time of enrollment at UCR Test scores from the Scholastic Assessment Test (SAT) or American College Test (ACT) and three required College Board Achievement Tests are also used to determine eligibility for admission. Continuation in the Program for each succeeding year is decided by a review of academic performance in combination with a personal evaluation of each student based upon extensive faculty-student contact. This allows for evaluating students as individuals with regard to their potential for becoming physicians. UCR students may also transfer into the Biomedical Sciences Program up until the end of their sophomore year if they have 1. Taken all the required courses (see Sample Program) 2. Carried an average academic load of approximately 48 quarter units per year 3. Obtained approval from the Premedical Advancement Committee of the Division of Biomedical Sciences. UCR students interested in transferring into the Biomedical Sciences major are encouraged to contact the Divisional Program Counselor. During the first three years, students complete a core of premedical courses in the biological and physical sciences and introductory courses in biomedical ethics and medical care, as well as electives in the social sciences and humanities. At the conclusion of the third undergraduate year, students are selected for continuation in the medical school phase of the Program. The admissions process involves consideration of the student's record of scholarship, of demonstrated aptitude for a commitment to medicine, of activities outside of the academic setting, of interaction with and compassion for others, of leadership qualifications, and of general personality traits that best characterize the physician. The Admissions Committee evaluates academic transcripts, MCAT scores, letters of recommendation, reports from the student's faculty advisors and from other faculty, a statement from the student and reports from special faculty interviewers. The total information is reviewed and advancement to the medical phase for each student is determined by vote of all members of the Admissions Committee. Beginning with the fourth year those students advanced to the medical school phase of the program are enrolled concurrently at UCR and the UCLA School of Medicine while still in residence at UCR. Students take course work in human anatomy, pathology, physiology, Doctoring 1, medical microbiology, and neurosciences. Students will continue their fifth year program of clinical studies, pharmacology, and patient relations at UCR. After their fifth year they transfer to the UCLA School of Medicine and complete the last two years of M.D. requirements. They also receive the Bachelor of Science degree from UCR after the fourth year in the program. Those students who do not continue in the accelerated program have additional opportunities to pursue careers in the health sciences. For example, after earning a B.S. degree they would be well qualified for application for admission to any four-year medical school, including the UCLA School of Medicine. The Biomedical Sciences Program also qualifies students for alternate possibilities such as pursuing graduate study for an M.S. or Ph.D. degree in any of the health-related sciences. UNIVERSITY REQUIREMENTS General University requirements are Universitywide requirements which all undergraduates must satisfy. See the Undergraduate Studies section of this catalog for a complete listing. COLLEGE REQUIREMENTS Students must fulfill all breadth requirements of the College of Natural and Agricultural Sciences for the B.S. degree. See Degree Requirements under College of Natural and Agricultural Sciences in the Undergraduate Studies section of this catalog. See the Biomedical Sciences Program office for courses that fulfill the Humanities and Social Sciences breadth requirement. PROGRAM REQUIREMENTS The sample programs shown below meet both college breadth and major requirements. Special requirements of the Program are as follows: 1. The Humanities and Social Sciences portions of the College Breadth requirements must be met within the student's first three years at UCR. 2. Students must complete two upper-division courses (4 units each) in the Humanities and Social Sciences in addition to those used to satisfy the College requirements. These courses may not be taken S/NC. Courses used to fulfill the Behavioral Sciences requirement (see 3 below) and BMSC 103 may not be used to meet this requirement. 3. Students must complete a one-quarter elective course in Behavioral Sciences dealing with the adjustment of the individual to society and/or relationships of science and medicine to society. This requirement can be met by taking one of the following 4-unit courses: ANTH 106, ANTH 133, ANTH 162; ETST 164/HMDV 164/PSYC 164, ETST 167/ PSYC 167, ETST 168/PSYC 168, HMDV 116/EDUC 116, HMDV 117/EDUC 117, HMDV 174/SOC 174, PSYC 140, PSYC 150, PSYC 151, PSYC 152, PSYC 153, PSYC 155, PSYC 160, PSYC 178, SOC 173. This course may not be taken S/NC, but may satisfy a portion of the College breadth requirements in Humanities and Social Sciences. 4. With respect to elective courses, Biomedical Sciences majors should not duplicate any subject material which is covered in the medical phase (years 4-7) of the Program (e.g., human physiology, immunology, genetics, physiological psychology). 5. Students must maintain at least a 3.00 cumulative grade point average for their freshman year to qualify for advancement into the second year of the program. A minimum grade point average of 3.3 is required to advance into the third year of the program. 6. By the end of year 3 of the program, Biomedical Sciences majors should have accumulated a minimum total of 143 academic units. Students must maintain an average of 16 units per quarter; units taken prior to enrolling at UCR or during summer sessions cannot be included. 7. No more than 6 units of undergraduate research (BMSC 097 or BMSC 197L) may be counted towards the major. 8. Courses listed in the sample program below are to be taken according to the indicated schedule. Students not selected for continuation in the medical school phase of the accelerated program may change to another major in the College of Natural and Agricultural Sciences and complete the course requirements for that major in the fourth year. Students are required to consult regularly with the faculty advisor with whom they design their individualized course programs according to the outline given in the sample program. Sample Program
Additional information may be requested by writing to the Program Counselor or by calling (909) 787-4333.
Description under Biochemistry. BIOL 111. Cell Biology. (4) F Description under Biology. BIOL 115. Human Genetics. (3) S Description under Biology. BIOL 121A. General Bacteriology and Microbiology. (3) F Description under Biology. BIOL 169. Human Growth and Development. (3) W Description under Biology. CHEM 112A-CHEM 112B-CHEM 112C. Organic Chemistry. (4-4-4) Year Description under Chemistry. PHIL 188. Biomedical Ethics. (4) W Description under Philosophy. STAT 105. Statistics for Biomedical Sciences. (2) F Description under Statistics. BMSC 100. Introduction to Medical Care. (2) Lecture, one hour; discussion, one hour. Prerequisite(s): third-year standing in the Biomedical Sciences Program. Consideration of the modern health care system. The course will include patient demonstrations and visits to primary care clinics, to operating and emergency rooms, to mental health facilities, and to private physicians' offices. These will be in small group sessions conducted in local hospital facilities. Graded Satisfactory (S) or No Credit (NC). Ewin, Sallis BMSC 103. Behavioral Sciences. (4) Lecture, four hours. Prerequisite(s): BIOL 005A, BIOL 005B, STAT105; or consent of instructor. Introduction to models of human behavior and the mind, and the application of the scientific method to the study of behavior. Topics covered include cognition, development, personality, clinical psychology, social psychology, and research methods including research design and statistical analysis. Credit is awarded for only one of BMSC 103 or PSYC 103. Hammond BMSC 120. General Biochemistry Related to Biomedical Sciences. (4) Lecture, three hours; discussion, one hour. Prerequisite(s): BCH 100 with a grade of "C+" or better or BCH 110A-BCH 110B with grades of "C-" or better or consent of instructor. Lectures on biochemical and molecular aspects of modern endocrinology, nutrition, metabolic diseases, and blood chemistry. Emphasis is on relation of the above topics to medicine. The discussion sections are used for presentations on topical medical problems. Although the course is designed specifically for the curriculum of the Biomedical Sciences Program, it may be appropriate for students in other departments. Cross-listed with BCH 120. Henry, Luben, Norman BMSC 194. Independent Reading. (1-2) Discussion, one hour; research, two to three hours. Prerequisite(s): upper-division standing and consent of instructor and Divisional Dean. Independent study involving library projects on topics related to Biomedical Sciences. Independent study will be conducted under faculty supervision. A written report to be graded Satisfactory (S) or No Credit (NC) will be requested. Course is repeatable to a maximum of 4 units. BMSC 197L. Research for Undergraduates. (1-3) Laboratory, three to nine hours. Prerequisite(s): upper-division standing (completion of 90 quarter units) and consent of instructor. An introduction to the methods of research in biomedical sciences. The student will conduct investigation in an area of biomedical sciences under the supervision of a Division of Biomedical Sciences faculty member and submit a written report on his/her work. Course is repeatable. Lecture, two hours; laboratory, nine hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program, or consent of instructor. A detailed study of normal human anatomy as revealed by dissection. The significance of structure and of structural relationships will be examined as a basis for the study of clinical medicine. Leonard BMSC 201. Modern Methods in Biomedical Research. (3) Lecture, three hours. Prerequisite(s): graduate standing or consent of instructor. Theory and applications of methods and systems currently used in disease-related research of man and animals. Presented by faculty with expertise in the areas covering molecular, cellular, and genetic approaches to biomedical research. BMSC 202. Molecular Basis of Disease. (3) Lecture, two hours; discussion, one hour. Prerequisite(s): graduate standing or consent of instructor. Discussion of the molecular basis of disease with special emphasis on new developments and the broad application of approaches and techniques. Course is repeatable with consent of the student's advisory committee; may be applied only once toward core requirements. BMSC 205. Human Microscopic Anatomy. (5) Lecture, two hours; laboratory, nine hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program, or consent of instructor. In-depth study of the microscopic anatomy of normal human tissues and organs. The course will emphasize the morphological basis of physiology. Walker. BMSC 210A-BMSC 210B. Human Physiology. (4-4) Lecture, three hours; laboratory, three hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program, or consent of instructor. A detailed study of human organ system function. The course will consist of lectures and laboratory exercises dealing with the normal physiology of the cardiovascular, respiratory, renal and gastrointestinal systems and with the relationship of normal physiology to disease states. The laboratories will include experience in animal surgery and in the use of biological transducers and electronic recording equipment. Quinton, Lytle BMSC 220. Neurosciences. (5) Lecture, three hours; laboratory, six hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program or consent of instructor. Structure and function of the nervous system. This course emphasizes the interrelationships between anatomy, physiology, and biochemistry of the nervous system as a basis for understanding its function in health and disease. Baker, Cohen. BMSC 222 (E-Z). Special Topics in Biomedical Sciences. (2) Lecture, one hour; discussion, one hour. Prerequisite(s): graduate standing or consent of instructor. For BMSC 222V: BMSC 224 or BIOL 128 or consent of instructor. Oral presentations and intensive small-group discussion of selected topics in the area of special competence of each staff member. Course content emphasizes recent advances in the special topic area and varies accordingly. Course is repeatable. E. Basic Epitheliology. Lytle, Quinton. G. Regulation of Gene Expression. Straus. I. Hematopoiesis. J. Microbial Pathogenesis and Host-Pathogen Interactions. Schiller. L. Current Topics in Cell Biology. Walker. M. Hormone Action. Byus, Luben. N. Mechanisms of Steroid Hormones. Norman. O. Steroid Metabolism. Henry. P. Molecular Pharmacology. Johnson. Q. Mechanisms of Carcinogenesis. Byus. R. Cerebral Control of Visceral Functions. Baker. S. Synaptic Transmission. Ashe. U. Transport Physiology. Lytle. V. Advanced Immunology. W. Developmental Neurogenetics. X. Mutagenesis and Genetic Instability. Grosovsky. Y. Cancer Genetics. Z. Molecular Neurobiology. Cohen. BMSC 224. Medical Immunology. (4) Lecture, three hours; laboratory, four hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program, or consent of instructor. Introduction to the molecular and cellular basis of the human immune system including discussion of antibody structure/function and cell-mediated inflammatory reactions. This information will be integrated into concepts on the role of the immune system in host defense and various pathological disease conditions, including organ transplantation, autoimmunity, immunodeficiencies, and viral diseases. Laboratory sessions will cover topics in immunochemistry, hematology and diagnostic assays of immune competence. BMSC 225A-BMSC 225B. Medical Microbiology. (3-3) Lecture, two and three hours; laboratory, three and zero hours. Prerequisite(s): BMSC 224 or equivalent; fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program, or consent of instructor. A review of the major bacteria, viruses, fungi, and parasites pathogenic to man. Major mechanisms of microbial pathogenesis and the corresponding clinical manifestations, and the principles of prevention, diagnosis, and treatment of infectious diseases are presented. Laboratory exercises emphasize the methodology involved in the isolation and identification of these microorganisms. Schiller. BMSC 230A-BMSC 230B. General Pharmacology. (5-2) Lecture, five hours. Prerequisite(s): for BMSC 230B: BMSC 230A, fifth-year or M.S. or Ph.D. standing in Biomedical Sciences or consent of instructor. The principles of pharmacology and their relationship to clinical medicine. General areas considered are the major categories of drugs, mechanisms of drug action, toxicology, pharmacological basis of therapeutics, and the effects of drugs on mammalian organ systems. Graded In Progress (IP) until both BMSC 230A and BMSC 230B are completed, at which time a final, Satisfactory (S) or No Credit (NC) grade is assigned. Byus, Johnson BMSC 235A-BMSC 235B-BMSC 235C. Introduction to Psychiatry. (1-2-1) Lecture, one hour; for BMSC 235B: discussion, one hour. Prerequisite(s): BMSC 103; for BMSC 235B: BMSC 235A; for BMSC 235C: BMSC 235B; fifth-year standing in the Biomedical Sciences Program. A study of fundamental concepts of normal sexuality and major psychiatric illnesses. Topics include depression, functional psychoses, organic mental disorders, and anxiety disorders. Graded In Progress (IP) until the third quarter is completed, at which time a final, Satisfactory (S) or No Credit (NC) grade is assigned. Summerour BMSC 240. General Pathology. (3)Lecture, two hours; laboratory, three hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program or consent of instructor. Human pathology covering basic alterations in cellular morphology and function in disease and their biochemical and clinical correlates. Atkinson, Koett BMSC 241. Preventive Medicine and Epidemiology. (2) Lecture, one hour; seminar, one hour. Prerequisite(s): fifth-year standing in the Biomedical Sciences Program. Essentials of the epidemiological method and uses of epidemiology in medicine. Application of basic demographic and epidemiological statistics to the measurement of disease processes in populations. Graded Satisfactory (S) or No Credit (NC). Vadheim BMSC 245A. Pathophysiology of Disease. (12) Lecture, eight hours; discussion, three hours; laboratory, three hours. Prerequisite(s): BMSC 240; fifth-year standing in the Biomedical Sciences Program or consent of instructor. Covers clinical manifestations and pathophysiology of disease and clinical pharmacology. Topics include cardiology, pulmonary disease, hematology, oncology, and gastroenterology. Graded Satisfactory (S) or No Credit (NC). Loo BMSC 245B. Pathophysiology of Disease. (10) Lecture, six hours; discussion, three hours; laboratory, three hours. Prerequisite(s): BMSC 245A; fifth-year standing in the Biomedical Sciences Program or consent of instructor. Covers clinical manifestations and pathophysiology of disease and clinical pharmacology. Topics include infectious diseases, nephrology, and endocrinology. Graded Satisfactory (S) or No Credit (NC). Loo BMSC 245C. Pathophysiology of Disease. (5) Lecture, 35 hours per quarter; discussion, 15 hours per quarter. Prerequisite(s): BMSC 245A, BMSC 245B; fifth-year standing in the Biomedical Sciences Program or consent of instructor. Covers clinical manifestations and pathophysiology of disease and clinical pharmacology. Topics include neurology, rheumatology, musculoskeletal diseases, allergy and immunology, and genetics. Graded Satisfactory (S) or No Credit (NC). Loo BMSC 251. Colloquium in Biomedical Sciences. (1) Colloquium, one hour. Prerequisite(s): graduate standing in Biomedical Sciences or consent of instructor. Specialized discussions by staff and students of current research topics in biomedical sciences. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 252. General Seminar in Biomedical Sciences. (1) Seminar, one hour. Prerequisite(s): graduate standing. Oral presentations by staff and visiting scholars on current research topics in the field of biomedical sciences. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 254. Graduate Seminar in Biomedical Sciences. (1) Seminar, one hour. Prerequisite(s): graduate standing. Oral reports by graduate students on current research topics in biomedical sciences. Letter grades will be assigned to students who present a seminar; others will be graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 255A-BMSC 255B-BMSC 255C. Doctoring I. (3 1/2-3 1/2-3 1/2) Discussion, thirty-six hours per quarter, three hours per week, three hours per week; clinic, zero hours per quarter, fifteen hours per quarter, fifteen hours per quarter. Prerequisite(s): for BMSC 255B: BMSC 255A; for BMSC 255C: BMSC 255B; fourth-year standing in the Biomedical Sciences Program. Introduction to small-group discussion of clinical cases, using a problem-based learning format. Cases are chosen to introduce basic interviewing skills and performance of a normal physical examination and to reinforce material presented in other courses. Includes sessions in a clinical setting with a community physician preceptor. Graded Satisfactory (S) or No Credit (NC). Jafri BMSC 256A-BMSC 256B-BMSC 256C. Doctoring II. (5-5-2) Discussion, four, four, and one hour; clinic, three hours. Prerequisite(s): BMSC 255A-BMSC 255B-BMSC 255C; for BMSC 256B: BMSC 256A; for BMSC 256C: BMSC 256B; fifth-year standing in the Biomedical Sciences Program. Small-group discussion of clinical cases,using a problem-based learning format. Cases are chosen to introduce advanced interviewing skills and to teach differential diagnosis. Includes sessions in a clinical setting with a community physician preceptor. Graded Satisfactory(S) or No Credit (NC). Stemerman BMSC 257. Graduate Seminar in Cell, Molecular, and Developmental Biology. (1) Seminar, one hour. Prerequisite(s): graduate standing. Lectures by visiting scholars on current research in cell, molecular, and developmental biology. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. Cross-listed with BCH 257, BIOL 257, BPSC 257, ENTM 257, ENTX 257, NEM 257, NRSC 257, and PLPA 257. BMSC 270A-BMSC 270B-BMSC 270C. Introduction to Patient Care. (2-2-2) Seminar, two hours. Prerequisite(s): for BMSC 270B: BMSC 270A; for BMSC 270C: BMSC 270B; fifth-year standing in the Biomedical Sciences Program. Introduction to the principal methods of clinical interviewing and patient examination. Emphasis is placed on the techniques of medical history taking and on developing skills of physical diagnosis. Graded Satisfactory (S) or No Credit (NC). Van Holten BMSC 287. Colloquium in Neuroscience. (1) Colloquium, one hour. Prerequisite(s): graduate standing or consent of instructor. Oral reports on current research topics in neuroscience with presentations by visiting scholars, faculty, and students. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. Cross-listed with BCH 287, BIOL 287, CHEM 287, ENTM 287, NRSC 287, and PSYC 287. BMSC 289. Special Topics in Neuroscience. (2) Seminar, two hours. Prerequisite(s): graduate standing or consent of instructor. An interdisciplinary seminar consisting of student presentations and discussions of selected topics in neuroscience. Content and instructor(s) vary each time course offered. Letter grades will be assigned to students presenting formal seminars; others will be graded Satisfactory (S) or No Credit (NC). Course is repeatable. Cross-listed with BCH 289, BIOL 289, CHEM 289, ENTM 289, NRSC 289, and PSYC 289. Hatton, in charge. BMSC 290. Directed Studies. (1-6) Research, three to eighteen hours. Prerequisite(s): graduate standing in Biomedical Sciences or consent of instructor. Experimental or literature studies on specifically selected topics under direction of a staff member. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 297. Directed Research. (1-6) Research, three to eighteen hours. Prerequisite(s): graduate standing in Biomedical Sciences or consent of instructor. Directed research in biomedical sciences performed prior to advancement to candidacy in preparation for dissertation projects. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 299. Research for Dissertation. (1-12) Research, three to thirty-six hours. Prerequisite(s): graduate standing in Biomedical Sciences or consent of instructor. Original research in the area selected for the advanced degree. Graded Satisfactory (S) or No Credit (NC). Course is repeatable.
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