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UC Riverside
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2002-2003 General Catalog
University of California, Riverside
BIOMEDICAL SCIENCES
Subject abbreviation: BMSC
Faculty | Program
Undergraduate Curricula | Graduate Curricula Undergraduate Course | Graduate Courses | Professional Course Michael B. Stemerman, M.D.,
Professors
UCR/UCLA THOMAS HAIDER PROGRAM IN BIOMEDICAL SCIENCES The Biomedical Sciences Program is an innovative approach to medical education developed by the University of California, Riverside, the UCLA School of Medicine and the clinically affiliated medical centers in the surrounding communities of Riverside and San Bernardino. It offers highly qualified students the opportunity to earn the M.D. degree in seven years instead of eight. It emphasizes the education of physicians who deal with the entire spectrum of disease diagnosis and treatment. Moreover, it provides a social and cultural background for its participants by including electives in the humanities and in the social and behavioral sciences as part of the curriculum. Changes to the Biomedical Sciences Program application procedure are being considered for Fall 2003 admission. Check biomedupdate.ucr.edu or contact the program office for current information. The Biomedical Sciences Program admits freshmen qualified for entrance into the University of California. Admission is granted to high school graduates entering UCR in the fall quarter. In addition, high school applicants to the UCR/UCLA Thomas Haider Program in Biomedical Sciences must have demonstrated a high level of scholarship in high school so as to provide a strong foundation for undertaking the rigorous, accelerated, first-year curriculum. Admission is also subject to the following criteria:
Test scores from the SAT or American College Test (ACT) and three required College Board Achievement Tests are also used to determine eligibility for admission. Continuation in the program for each succeeding year is decided primarily by a review of academic performance. UCR students may also transfer into the Biomedical Sciences Program up until the end of their sophomore year if they have
UCR students interested in transferring into the Biomedical Sciences major are encouraged to contact the Divisional Program Advisor. During the first three years, students complete a core of premedical courses in the biological and physical sciences and introductory courses in biomedical ethics and medical care, as well as electives in the social sciences and humanities. At the conclusion of the third undergraduate year, students are selected for continuation in the medical school phase of the program. The admissions process involves consideration of the student's record of scholarship, demonstrated aptitude for a commitment to medicine, activities outside of the academic setting, interaction with and compassion for others, leadership qualifications, and general personality traits that best characterize the physician. The admissions committee evaluates academic transcripts, MCAT scores, letters of recommendation, a statement from the student and reports from special faculty interviewers. The total information is reviewed and advancement to the medical phase for each student is determined by vote of all members of the admissions committee. Beginning with the fourth year, those students advanced to the medical school phase of the program are enrolled concurrently at UCR and the UCLA School of Medicine while still in residence at UCR. Students take course work in human anatomy, pathology, physiology, Doctoring 1, medical microbiology, and neurosciences. Students continue their fifth year program of clinical studies, pharmacology, and patient relations at UCR. After their fifth year they transfer to the UCLA School of Medicine and complete the last two years of M.D. requirements. They also receive the B.S. degree from UCR after the fourth year in the program. Those students who do not continue in the accelerated program have additional opportunities to pursue careers in the health sciences. For example, after earning a B.S. degree they would be well qualified for application for admission to any four-year medical school, including the UCLA School of Medicine. The Biomedical Sciences Program also qualifies students for alternate possibilities such as pursuing graduate study for an M.S. or Ph.D. degree in any of the health-related sciences. Degree Requirements University Requirements See the Undergraduate Studies section for requirements that all students must satisfy. College Requirements See Degree Requirements, College of Natural and Agricultural Sciences, in the Undergraduate Studies Section, for requirements that students in the B.S. program must satisfy. See the Biomedical Sciences Program office for courses that fulfill the Humanities and Social Sciences breadth requirement. Program Requirements The required program in Biomedical Sciences shown below meets both college breadth and Major Requirements. Special requirements of the program are as follows:
Students not selected for continuation in the medical school phase of the accelerated program change to another major in the College of Natural and Agricultural Sciences and complete the course requirements for that major in the fourth year. Students in the Biomedical Sciences Program are urged to consult periodically with a faculty advisor.
Additional information may be requested by writing to the program counselor or by calling (909) 787-4333. BMSC 097. Research Tutorial in Biomedical Sciences. (1-2) Laboratory, three to six hours. Prerequisite(s): grade point of 3.0 and consent of instructor. Laboratory tutorial in research related to biomedical sciences. To provide laboratory experience in the areas of physiology, microbiology, molecular biology, pharmacology, cell biology, immunology, biochemistry for exceptional lower-division students. A written report is required at the end of each quarter. Graded Satisfactory (S) or No Credit (NC). May be repeated for up to 6 units. UPPER-DIVISION COURSES BCH 110A, BCH 110B, BCH 110C. General Biochemistry. (4, 4, 4) Description under Biochemistry. BIOL 115. Human Genetics. (3) S Description under Biology. BIOL 121A/MCBL 121A. General Bacteriology and Microbiology. (4) F Description under Biology. CBNS 169. Human Growth and Development. (4) W Description under Neuroscience. CHEM 112A, CHEM 112B, CHEM 112C. Organic Chemistry. (4, 4, 4) Description under Chemistry. PHIL 167. Biomedical Ethics. (4) W Description under Philosophy. STAT 105. Statistics for Biomedical Sciences. (2) F Description under Statistics. BMSC 100. Introduction to Medical Care. (2) Lecture, one hour; discussion, one hour. Prerequisite(s): third-year standing in the Biomedical Sciences Program. Consideration of the modern health care system. The course will include patient demonstrations and visits to primary care clinics, to operating and emergency rooms, to mental health facilities, and to private physicians' offices. These will be in small group sessions conducted in local hospital facilities. Graded Satisfactory (S) or No Credit (NC). Johnson BMSC 103. Behavioral Sciences. (4) Lecture, four hours. Prerequisite(s): BIOL 005A, BIOL 005B, STAT 105; or consent of instructor. Introduction to models of human behavior and the mind, and the application of the scientific method to the study of behavior. Topics covered include cognition, development personality, clinical psychology, social psychology, and research methods including research design and statistical analysis. BMSC 120. General Biochemistry Related to Biomedical Sciences. (4) Lecture, three hours; discussion, one hour. Prerequisite(s): BCH 100 with a grade of "C+" or better or BCH 110B with a grade of "C-" or better or consent of instructor. Lectures on biochemical and molecular aspects of modern endocrinology, nutrition, metabolic diseases, and blood chemistry. Emphasis is on relation of the above topics to medicine. The discussion sections are used for presentations on topical medical problems. Although the course is designed specifically for the curriculum of the Biomedical Sciences Program, it may be appropriate for students in other departments. Cross-listed with BCH 120. Henry, Luben, Norman BMSC 194. Independent Reading. (1-2) Discussion, one hour; research, two to three hours. Prerequisite(s): upper-division standing and consent of instructor and Divisional Dean. Independent study involving library projects on topics related to Biomedical Sciences. Independent study will be conducted under faculty supervision. A written report to be graded Satisfactory (S) or No Credit (NC) will be requested. Course is repeatable to a maximum of 4 units. BMSC 197L. Research for Undergraduates. (1-3) Laboratory, three to nine hours. Prerequisite(s): upper-division standing (completion of 90 quarter units) and consent of instructor. An introduction to the methods of research in biomedical sciences. The student will conduct investigation in an area of biomedical sciences under the supervision of a Division of Biomedical Sciences faculty member and submit a written report on his/her work. Course is repeatable. BMSC 200A. Human Gross Anatomy. (5) Lecture, two hours; laboratory, nine hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program, or consent of instructor. A detailed study of normal human anatomy as revealed by dissection. The significance of structure and of structural relationships is examined as a basis for the study of clinical medicine. Colgan BMSC 200B. Human Gross Anatomy. (5) Lecture, two hours; laboratory, nine hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program, or consent of instructor. A detailed study of normal human anatomy as revealed by dissection. The significance of structure and of structural relationships is examined as a basis for the study of clinical medicine. Colgan BMSC 201. Modern Methods in Biomedical Research. (3) Lecture, three hours. Prerequisite(s): graduate standing or consent of instructor. Theory and applications of methods and systems currently used in disease-related research of man and animals. Presented by faculty with expertise in the areas covering molecular, cellular, and genetic approaches to biomedical research. BMSC 202. Molecular Basis of Disease. (3) Lecture, two hours; discussion, one hour. Prerequisite(s): graduate standing or consent of instructor. Discussion of the molecular basis of disease with special emphasis on new developments and the broad application of approaches and techniques. Course is repeatable with consent of the student's advisory committee; may be applied only once toward core requirements. BMSC 205. Human Microscopic Anatomy. (5) Lecture, two hours; laboratory, nine hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program, or consent of instructor. In-depth study of the microscopic anatomy of normal human tissues and organs. The course will emphasize the morphological basis of physiology. DeFea, Walker BMSC 210A. Human Physiology. (4) Lecture, three hours; laboratory, three hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program, or consent of instructor. A detailed study of human organ system function. Consists of lectures, discussions, and laboratory exercises dealing with the physiology of the cardiovascular, respiratory, renal, and gastrointestinal systems and with the relationship of normal physiology to disease states. Laboratories include case discussions and problem-solving exercises that emphasize clinical connections. Graded In Progress (IP) until BMSC 210A and BMSC 210B are completed, at which time a final, letter grade is assigned. Lytle BMSC 210B. Human Physiology. (4) Lecture, three hours; laboratory, three hours. Prerequisite(s): BMSC 210A; fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program, or consent of instructor. A detailed study of human organ system function. Consists of lectures, discussions, and laboratory exercises dealing with the physiology of the cardiovascular, respiratory, renal, and gastrointestinal systems and with the relationship of normal physiology to disease states. Laboratories include case discussions and problem-solving exercises that emphasize clinical connections. Quinton BMSC 220. Neurosciences. (5) Lecture, three hours; laboratory, six hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program or consent of instructor. Structure and function of the nervous system. This course emphasizes the interrelationships between anatomy, physiology, and biochemistry of the nervous system as a basis for understanding its function in health and disease. Colgan, I. Ethell, D. Ethell BMSC 222 (E-Z). Special Topics in Biomedical Sciences. (2) Lecture, one hour; discussion, one hour. Prerequisite(s): graduate standing or consent of instructor. For BMSC 222V: BMSC 224 or BIOL 128/NRSC 128 or consent of instructor. Oral presentations and intensive small-group discussion of selected topics in the area of special competence of each staff member. Course content emphasizes recent advances in the special topic area and varies accordingly. Course is repeatable. E. Basic Epitheliology. Lytle, Quinton
BMSC 224. Medical Immunology. (4) Lecture, three hours; laboratory, four hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program, or M.S./ Ph.D. status in the Biomedical Sciences Graduate Program, or consent of instructor. Introduction to the molecular and cellular basis of the human immune system including discussion of antibody structure/function and cell-mediated inflammatory reactions. This information will be integrated into concepts on the role of the immune system in host defense and various pathological disease conditions, including organ transplantation, autoimmunity, immunodeficiencies, and viral diseases. Laboratory sessions will cover topics in immunochemistry, hematology and diagnostic assays of immune competence. Owen-Schaub BMSC 225A. Medical Microbiology. (3) Lecture, thirty hours per quarter. Prerequisite(s): BMSC 224 or equivalent; fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program or consent of instructor. Reviews the major bacteria that are pathogenic to humans. Presents the major mechanisms of bacterial pathogenesis the corresponding clinical manifestations, and the principles of prevention, diagnosis, and treatment of bacterial infectious diseases. Schiller BMSC 225B. Medical Microbiology. (3) Lecture, three hours; laboratory, twenty hours per quarter. Prerequisite(s): BMSC 224 or equivalent; fourth-year standing in the Biomedical Sciences Program, or M.S./Ph.D. status in the Biomedical Sciences Graduate Program, or consent of instructor.~Reviews the major viruses, fungi, and parasites that are pathogenic to humans. Presents the major mechanisms of microbial pathogenesis, the corresponding clinical manifestations, and the principles of prevention, diagnosis, and treatment of infectious diseases. Laboratory exercises emphasize the methodology involved in the isolation and identification of pathogenic bacteria. Schiller BMSC 230A. General Pharmacology. (5) Lecture, forty-nine hours per quarter. Prerequisite(s): fifth-year or M.S. or Ph.D. standing in Biomedical Sciences or consent of instructor. A study of the principles of pharmacology and their relationship to clinical medicine. Considers the major categories of drugs, mechanisms of drug action, toxicology, the pharmacological basis of therapeutics, and the effects of drugs on mammalian organ systems. Graded In Progress (IP) until BMSC 230A, BMSC 230B, and BMSC 230C are completed, at which time a final, Satisfactory (S) or No Credit (NC) grade is assigned. Byus, Johnson, Shyy BMSC 230B. General Pharmacology. (0.5) Lecture, five hours per quarter. Prerequisite(s): BMSC 230A; fifth-year or M.S. or Ph.D. standing in Biomedical Sciences or consent of instructor. A study of the principles of pharmacology and their relationship to clinical medicine. Considers the major categories of drugs, mechanisms of drug action, toxicology, the pharmacological basis of therapeutics, and the effects of drugs on mammalian organ systems. Graded In Progress (IP) until BMSC 230A, BMSC 230B, and BMSC 230C are completed, at which time a final, Satisfactory (S) or No Credit (NC) grade is assigned. Byus, Johnson, Shyy BMSC 230C. General Pharmacology. (0.5) Lecture, eight hours per quarter. Prerequisite(s): BMSC 230B; fifth-year or M.S. or Ph.D. standing in Biomedical Sciences or consent of instructor. A study of the principles of pharmacology and their relationship to clinical medicine. Considers the major categories of drugs, mechanisms of drug action, toxicology, the pharmacological basis of therapeutics, and the effects of drugs on mammalian organ systems. Graded Satisfactory (S) or No Credit (NC). Byus, Johnson, Shyy BMSC 235A. Introduction to Psychiatry. (2) Lecture, two hours. Prerequisite(s): BMSC 103; fifth-year standing in the Biomedical Sciences Program. A study of fundamental concepts of normal and abnormal sexuality and major psychiatric illnesses. Topics include depression, functional psychoses, organic mental disorders, and anxiety disorders. Graded In Progress (IP) until both BMSC 235A and BMSC 235B are completed, at which time a final, Satisfactory (S) or No Credit (NC) grade is assigned. Summerour BMSC 235B. Introduction to Psychiatry. (2) Lecture, two hours. Prerequisite(s): BMSC 235A; fifth-year standing in the Biomedical Sciences Program. A study of fundamental concepts of normal and abnormal sexuality and major psychiatric illnesses. Topics include depression, functional psychoses organic mental disorders, and anxiety disorders. Graded Satisfactory (S) or No Credit (NC). Summerour BMSC 240. General Pathology. (3) Lecture, two hours; laboratory, three hours. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program or consent of instructor. Human pathology covering basic alterations in cellular morphology and function in disease and their biochemical and clinical correlates. Atkinson BMSC 241. Preventive Medicine and Epidemiology. (2) Lecture, one hour; seminar, one hour. Prerequisite(s): fifth-year standing in the Biomedical Sciences Program. Essentials of the epidemiological method and uses of epidemiology in medicine. Application of basic demographic and epidemiological statistics to the measurement of disease processes in populations. Graded Satisfactory (S) or No Credit (NC). Vadheim BMSC 245A. Pathophysiology of Disease. (12) Lecture, eight hours; discussion, three hours; laboratory, three hours. Prerequisite(s): BMSC 240; fifth-year standing in the Biomedical Sciences Program or consent of instructor. Covers clinical manifestations and pathophysiology of disease and clinical pharmacology. Topics include cardiology, pulmonary disease, hematology, oncology, and gastroenterology. Graded Satisfactory (S) or No Credit (NC). Loo BMSC 245B. Pathophysiology of Disease. (10) Lecture, six hours; discussion, three hours; laboratory, three hours. Prerequisite(s): BMSC 245A; fifth-year standing in the Biomedical Sciences Program or consent of instructor. Covers clinical manifestations and pathophysiology of disease and clinical pharmacology. Topics include infectious diseases, nephrology, and endocrinology. Graded Satisfactory (S) or No Credit (NC). Loo BMSC 245C. Pathophysiology of Disease. (5) Lecture, thirty-five hours per quarter; discussion, fifteen hours per quarter. Prerequisite(s): BMSC 245A, BMSC 245B; fifth-year standing in the Biomedical Sciences Program or consent of instructor. Covers clinical manifestations and pathophysiology of disease and clinical pharmacology. Topics include neurology, rheumatology, musculoskeletal diseases, allergy and immunology, and genetics. Graded Satisfactory (S) or No Credit (NC). Loo BMSC 251. Colloquium in Biomedical Sciences. (1) Colloquium, one hour. Prerequisite(s): graduate standing in Biomedical Sciences or consent of instructor. Specialized discussions by staff and students of current research topics in biomedical sciences. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 252. General Seminar in Biomedical Sciences. (1) Seminar, one hour. Prerequisite(s): graduate standing. Oral presentations by staff and visiting scholars on current research topics in the field of biomedical sciences. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 254. Graduate Seminar in Biomedical Sciences. (1) Seminar, one hour. Prerequisite(s): graduate standing. Oral reports by graduate students on current research topics in biomedical sciences. Letter grades will be assigned to students who present a seminar; others will be graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 255A. Doctoring I. (3 1/2) Discussion, thirty-six hours per quarter. Prerequisite(s): fourth-year standing in the Biomedical Sciences Program. Introduction to small-group discussion of clinical cases, using a problem-based learning format. Cases are chosen to introduce basic interviewing skills and performance of a normal physical examination and to reinforce material presented in other courses. Includes sessions in a clinical setting with a community physician preceptor. Graded Satisfactory (S) or No Credit (NC). Jafri BMSC 255B. Doctoring I. (3 1/2) Discussion, three hours per week; clinic, fifteen hours per quarter. Prerequisite(s): BMSC 255A; fourth-year standing in the Biomedical Sciences Program. Introduction to small-group discussion of clinical cases, using a problem-based learning format. Cases are chosen to introduce basic interviewing skills and performance of a normal physical examination and to reinforce material presented in other courses. Includes sessions in a clinical setting with a community physician preceptor. Graded Satisfactory (S) or No Credit (NC). Jafri BMSC 255C. Doctoring I. (3 1/2) Discussion, three hours per week; clinic, fifteen hours per quarter. Prerequisite(s): BMSC 255B; fourth-year standing in the Biomedical Sciences Program. Introduction to small-group discussion of clinical cases, using a problem-based learning format. Cases are chosen to introduce basic interviewing skills and performance of a normal physical examination and to reinforce material presented in other courses. Includes sessions in a clinical setting with a community physician preceptor. Graded Satisfactory (S) or No Credit (NC). Jafri BMSC 256A. Doctoring II. (5) Discussion, four hours; clinic, three hours. Prerequisite(s): BMSC 255A, BMSC 255B, BMSC 255C; fifth-year standing in the Biomedical Sciences Program. Involves small-group discussions of clinical cases, using a problem-based learning format. Cases are chosen to introduce advanced interviewing skills and to teach differential diagnosis. Includes sessions in a clinical setting with a community physician preceptor. Graded Satisfactory (S) or No Credit (NC). Hunt BMSC 256B. Doctoring II. (5) Discussion, four hours; clinic, three hours. Prerequisite(s): BMSC 255A, BMSC 255B, BMSC 255C, BMSC 256A; fifth-year standing in the Biomedical Sciences Program. Involves small-group discussions of clinical cases, using a problem-based learning format. Cases are chosen to introduce advanced interviewing skills and to teach differential diagnosis. Includes sessions in a clinical setting with a community physician preceptor. Graded Satisfactory (S) or No Credit (NC). Hunt BMSC 256C. Doctoring II. (2) Discussion, one hour; clinic, three hours. Prerequisite(s): BMSC 255A, BMSC 255B, BMSC 255C, BMSC 256B; fifth-year standing in the Biomedical Sciences Program. Involves small-group discussions of clinical cases, using a problem-based learning format. Cases are chosen to introduce advanced interviewing skills and to teach differential diagnosis. Includes sessions in a clinical setting with a community physician preceptor. Graded Satisfactory (S) or No Credit (NC). Hunt BMSC 270A. Introduction to Patient Examination. (2) Seminar, two hours. Prerequisite(s): fifth-year standing in the Biomedical Sciences Program. Introduction to the principal methods of clinical interviewing and patient examination. Emphasis is placed on the techniques of medical history taking and on developing skills of physical diagnosis. Graded Satisfactory (S) or No Credit (NC). Van Holten BMSC 270B. Introduction to Patient Examination. (2) Seminar, two hours. Prerequisite(s): BMSC 270A; fifth-year standing in the Biomedical Sciences Program. Introduction to the principal methods of clinical interviewing and patient examination. Emphasis is placed on the techniques of medical history taking and on developing skills of physical diagnosis. Graded Satisfactory (S) or No Credit (NC). Van Holten BMSC 270C. Introduction to Patient Examination. (2) Seminar, two hours. Prerequisite(s): BMSC 270B; fifth-year standing in the Biomedical Sciences Program. Introduction to the principal methods of clinical interviewing and patient examination. Emphasis is placed on the techniques of medical history taking and on developing skills of physical diagnosis. Graded Satisfactory (S) or No Credit (NC). Van Holten BMSC 287. Colloquium in Neuroscience. (1) Colloquium, one hour. Prerequisite(s): graduate standing or consent of instructor. Oral reports on current research topics in neuroscience with presentations by visiting scholars, faculty, and students. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. Cross-listed with BCH 287, BIOL 287, CHEM 287, NRSC 287, and PSYC 287. Hatton in charge BMSC 289. Special Topics in Neuroscience. (2) Seminar, two hours. Prerequisite(s): graduate standing or consent of instructor. An interdisciplinary seminar consisting of student presentations and discussions of selected topics in neuroscience. Content and instructor(s) vary each time course offered. Letter grades will be assigned to students presenting formal seminars; others will be graded Satisfactory (S) or No Credit (NC). Course is repeatable. Cross-listed with BCH 289, BIOL 289, CHEM 289, ENTM 289, NRSC 289, and PSYC 289. Hatton in charge BMSC 290. Directed Studies. (1-6) Research, three to eighteen hours. Prerequisite(s): graduate standing in Biomedical Sciences or consent of instructor. Experimental or literature studies on specifically selected topics under direction of a staff member. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 297. Directed Research. (1-6) Research, three to eighteen hours. Prerequisite(s): graduate standing in Biomedical Sciences or consent of instructor. Directed research in biomedical sciences performed prior to advancement to candidacy in preparation for dissertation projects. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 299. Research for Dissertation. (1-12) Research, three to thirty-six hours. Prerequisite(s): graduate standing in Biomedical Sciences or consent of instructor. Original research in the area selected for the advanced degree. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 302. Directed Teaching. (2) Practicum, six hours. Prerequisite(s): graduate standing in Biomedical Sciences. Supervised teaching in medical school courses. Required for all Biomedical Sciences graduate students. Fulfills the teaching portion of the teaching requirement for the Ph.D.; four units are required for the Ph.D. Graded Satisfactory (S) or No Credit (NC). Course is repeatable to a maximum of 6 units. 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