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2002-03 front (PDF)
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2002-03 back (PDF)
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2002-2003 General Catalog
University of California, Riverside

CELL, MOLECULAR, AND DEVELOPMENTAL BIOLOGY

Subject abbreviation: CMDB


Prudence Talbot, Ph.D., Chair
Graduate Program, 1151 Batchelor Hall
(800) 735-0717 or (909) 787-5913
www.cell.ucr.edu

Faculty E-mails

Professors
Michael Adams, Ph.D. (Cell Biology and Neuroscience/ Entomology)
John Ashe, Ph.D. (Cell Biology and Neuroscience/Psychology)
Julia Bailey-Serres, Ph.D. (Botany and Plant Sciences)
James Baldwin, Ph.D. (Nematology)
Nancy Beckage, Ph.D. (Entomology/Cell Biology and Neuroscience)
Richard Cardullo, Ph.D. (Biology)
Darleen DeMason, Ph.D. (Botany and Plant Sciences)
David Eastmond, Ph.D. (Cell Biology and Neuroscience)
Brian Federici, Ph.D. (Entomology)
Dennis Focht, Ph.D. (Plant Pathology)
Daniel Gallie, Ph.D. (Biochemistry)
Sarjeet S. Gill, Ph.D. (Cell Biology and Neuroscience)
Andrew Grosovsky, Ph.D. (Cell Biology and Neuroscience)
Leah Haimo, Ph.D. (Biology)
Glenn Hatton, Ph.D. (Cell Biology and Neuroscience)
Robert Heath, Ph.D. (Botany and Plant Sciences)
Helen Henry, Ph.D. (Biochemistry)
Anthony H.C. Huang, Ph.D. (Botany and Plant Sciences)
Bradley Hyman, Ph.D. (Biology)
Elizabeth M. Lord, Ph.D. (Botany and Plant Sciences)
Richard Luben, Ph.D. (Biomedical Sciences)
Thomas Miller, Ph.D. (Entomology)
Anthony Norman, Ph.D. (Biochemistry/Biomedical Sciences)
Eugene Nothnagel, Ph.D. (Botany and Plant Sciences)
Laurie Owen-Schaub, Ph.D. (Biomedical Sciences)
Alexander Raikhel (Entomology)
Natasha Raikhel (Botany and Plant Sciences)
Neil Schiller, Ph.D. (Biomedical Sciences)
Stephen Spindler, Ph.D. (Biochemistry)
B. Glenn Stanley, Ph.D. (Cell Biology and Neuroscience/Psychology)
Daniel Straus, Ph.D. (Biomedical Sciences)
Prudence Talbot, Ph.D. (Cell Biology and Neuroscience)
Linda Walling, Ph.D. (Botany and Plant Sciences)
Shizhong Xu, Ph.D. (Botany and Plant Sciences)
Raphael Zidovetzki, Ph.D. (Cell Biology and Neuroscience)
Professors Emeriti
Salomon Bartnicki-Garcia, Ph.D. (Plant Pathology)
Irwin W. Sherman, Ph.D. (Biology)
Associate Professors
Peter W. Atkinson, Ph.D. (Entomology)
Elizabeth Bray, Ph.D. (Botany and Plant Sciences)
Margarita Currás-Collazo, Ph.D. (Cell Biology and Neuroscience)
Scott N. Currie, Ph.D. (Cell Biology and Neuroscience)
Howard Judelson, Ph.D. (Plant Pathology)
Christian Lytle, Ph.D. (Biomedical Sciences)
Manuela Martins-Green, Ph.D. (Cell Biology and Neuroscience)
Frances Sladek, Ph.D. (Cell Biology and Neuroscience)
Assistant Professors
Jeffrey B. Bachant, Ph.D. (Cell Biology and Neuroscience)
Katherine Borkovich, Ph.D. (Plant Pathology)
Kathryn DeFea, Ph.D. (Biomedical Sciences)
Shou-Wei Ding, Ph.D. (Plant Pathology)
Douglas Ethell, Ph.D. (Biomedial Sciences)
Iryna Ethell, Ph.D. (Biomedical Sciences
Isgouhi Kaloshian, Ph.D. (Nematology)
Paul Larsen, Ph.D. (Biochemistry)
Sheri J. Lillard, Ph.D. (Chemistry)
Xuan Liu, Ph.D. (Biochemistry)
Ernest Martinez, Ph.D. (Biochemistry)
Dmitri Maslov, Ph.D. (Biology)
Constance I. Nugent, Ph.D. (Cell Biology and Neuroscience)
Mihri Ozkan, Ph.D. (Electrical Engineering/ Chemical and Environmental Engineering)
Vladimir Parpura, M.D., Ph.D. (Cell Biology and Neuroscience)
A.L.N. Rao, Ph.D. (Plant Pathology)
Patricia S. Springer, Ph.D. (Botany and Plant Sciences)
Willie J. Swanson, Ph.D. (Biology)
John P. Vogel, Ph.D. (Plant Pathology)
Stephan Wilkens, Ph.D. (Biochemistry)
Zhenbiao Yang, Ph.D. (Botany and Plant Sciences)

The Cell, Molecular, and Developmental Biology Graduate Program is an interdepartmental program offering M.S. and Ph.D. degrees to students seeking advanced training in these disciplines. The program focuses on the bridge between basic and applied research and on the interface between cell, molecular, and developmental biology. Participating faculty are drawn from numerous biological sciences departments whose research interests in cell, molecular, and developmental biology span biomedical to agricultural problems, and students in the program benefit from unique training opportunities.

Students seeking admission into the program should meet all general requirements of the Graduate Division as printed in the Graduate Studies section of this catalog. Applicants should have adequate undergraduate course work in chemistry (two years), physics (one year), calculus (one year), statistics (one course), biochemistry (one course), and biology (two years, including a course in genetics and two courses among cell, molecular, or developmental biology). Applicants with strong academic records but with deficiencies in preparation for graduate training may be admitted and need to rectify undergraduate deficiencies early in the first two years of residence.

Applicants must submit GRE General Test scores (verbal, quantitative and analytical).

GRADUATE PROGRAM

The program offers an M.S. degree, Plan I (Thesis), and a Ph.D. degree. Students enrolled in either degree program are expected to complete the following core of course work in cell, molecular, and developmental biology:

  1. One graduate-level course in cell biology (BIOL 200/CMDB 200, BPSC 237, or NRSC 200A/PSYC 200A)
  2. One graduate-level course in molecular biology (BIOL 201/CMDB 201, BCH 211, BPSC 231/BCH 231, BMSC 202, or NRSC 200B/PSYC 200B)
  3. One graduate-level course in developmental biology (BIOL 222, BPSC 232/BIOL 232, or ENTM 226)

Each student enrolls in the interdepartmental colloquium series in Cell, Molecular, and Developmental Biology (CMDB 257). Upon entry into the program, each student meets with a guidance committee, which recommends a course of study commensurate with the student's interests and background.

Master's Degree

Master's students complete core course work in cell, molecular, and developmental biology; enroll in at least one graduate seminar course in a specialized area in one of these fields; enroll in the interdepartmental colloquium series in Cell, Molecular, and Developmental Biology; and undertake a research project leading to a thesis. Each student must complete 36 units of course work, of which at least 24 units must be in the graduate series (200 level) in the biological sciences. No more than 12 units in the 290 series can be taken to fulfill the 24-unit requirement. Candidates for the M.S. degree must defend their thesis at a public oral presentation.

Doctoral Degree

Students enroll in one graduate course in cell, molecular, and developmental biology, in addition to the three core courses indicated in the description for the graduate program. Students enroll in graduate seminar courses in at least two areas among cell, molecular, or developmental biology and in the interdepartmental colloquium series in Cell, Molecular, and Developmental Biology. Each candidate undertakes a research project leading to a dissertation, and fulfills a two-quarter teaching requirement. Thirty-six units of 100- or 200-series courses must be taken, of which at least 24 units must be in the graduate series (200 level) in the biological sciences. A minimum of 16 units of course work not in the 290 series must be completed to fulfill the requirements for 24 units of graduate course work.

Doctoral students are advanced to candidacy following successful completion of written and oral qualifying examinations. Students write a proposal detailing the rationale, specific aims, and approaches to be undertaken for their proposed dissertation research prior to taking the oral qualifying examination. Ph.D. candidates must successfully defend their dissertation research in a public oral presentation.

Career Opportunities

There is a high demand in industry and academia for scientists with training in cell, molecular, and developmental biology. Students matriculating from the program are well trained in this field and successfully obtain positions in biotechnology, including biomedical and agricultural industries, and at colleges and universities nationwide.

Normative Time to M.S. Two years

Normative Time to Ph.D. Five years


GRADUATE COURSES

CMDB 200. Cell Biology. (4) Lecture, three hours; seminar, one hour. Prerequisite(s): BCH 110A or BCH 110B or equivalent (may be taken concurrently); BIOL 102 or equivalent; BIOL 113 or BIOL 114 or CBNS 101 or equivalent. An examination of the structure and function of eukaryotic cells and their components with emphasis on the key experiments that provide the foundation for our current knowledge. Covers topics such as cell membranes, intracellular trafficking, cell-to-cell interactions, motility, and the cytoskeleton. Cross-listed with BIOL 200.

CMDB 201. Molecular Biology. (4) Lecture, three hours; seminar, one hour. Prerequisite(s): BCH 110A or BCH 110B or equivalent (may be taken concurrently); BIOL 102 or equivalent; BIOL 107A or equivalent. Covers the structure and inheritance of genetic material, the regulation of gene expression at the cellular and molecular level including molecular mechanisms for regulation of gene transcription, posttranscriptional regulation at the level of messenger RNA stability, processing, editing and translation, methods for gene mapping, and positional cloning. Cross-listed with BIOL 201.

CMDB 202. Developmental Biology. (4) Lecture, three hours; discussion, one hour. Prerequisite(s): CBNS 101 or equivalent. An examination of development, beginning with the principles that underlie developmental studies of all multicellular organisms. Focuses on plants, insects, and fungi but introduces other model systems. Topics are taken from the current literature.

CMDB 250. Special Topics in Cell, Molecular, and Developmental Biology. (1-2) Seminar, one to two hours. Prerequisite(s): graduate standing. Oral presentations and intensive small-group discussion of selected topics in the area of special competence of each participant. Content emphasizes recent advances in the topic area and varies accordingly. Graded Satisfactory (S) or No Credit (NC). Course is repeatable.

CMDB 257. Seminar in Cell, Molecular, and Developmental Biology. (1) Seminar, one hour. Prerequisite(s): graduate standing. Lectures by visiting scholars on current research in cell, molecular, and developmental biology. Graded Satisfactory (S) or No Credit (NC). Course is repeatable.

CMDB 258. Graduate Student Seminar in Cell, Molecular, and Developmental Biology. (1) One one-day seminar. Prerequisite(s): graduate standing in Cell, Molecular, and Developmental Biology. An interdisciplinary seminar consisting of student presentations of original research and discussion of current research topics in cell, molecular, and developmental biology. Graded Satisfactory (S) or No Credit (NC). Course is repeatable.

CMDB 281 (E-Z). Seminar in Cell Development, Structure, and Function. (2) Seminar, two hours. Prerequisite(s): graduate standing; consent of instructor. Lectures, discussions, and demonstrations by students, faculty, and invited scholars on selected subjects concerned with the principles of cell development, structure, and function. E. Cell Biology; F. Molecular Biology; G. Developmental Biology. Segments are repeatable. Cross-listed with BIOL 281 (E-Z).

CMDB 290. Directed Studies. (1-6) Individual study, three to eighteen hours. Prerequisite(s): graduate standing; consent of instructor and graduate advisor. Individual study, directed by a faculty member, of specially selected topics in cell, molecular, and developmental biology. Graded Satisfactory (S) or No Credit (NC). Course is repeatable.

CMDB 292. Concurrent Analytical Studies in Cell, Molecular, and Developmental Biology. (2-4) Outside research, six to twelve hours. Prerequisite(s): graduate standing. Elected concurrently with an appropriate undergraduate course, but on an individual basis. Students are required to submit one or more graduate papers based on research or criticism related to the course. Graded Satisfactory (S) or No Credit (NC). Course is repeatable.

CMDB 297. Directed Research. (1-6) Outside research, three to eighteen hours. Prerequisite(s): graduate standing. Research and experimental studies conducted under the supervision of a faculty member on specially selected topics in cell, molecular, and developmental biology. Graded Satisfactory (S) or No Credit (NC). Course is repeatable.

CMDB 299. Research for the Thesis or Dissertation. (1-12) Outside research, three to thirty-six hours. Prerequisite(s): graduate standing. Original research in an area selected for the advanced degree. Graded Satisfactory (S) or No Credit (NC). Course is repeatable.


PROFESSIONAL COURSE

CMDB 301. Teaching of Cell, Molecular, and Developmental Biology at the College Level. (1)

Seminar, one hour. Prerequisite(s): graduate standing. A program of weekly meetings and individual formative evaluations required of new teaching assistants. Covers instructional methods and classroom/section activities most suitable for teaching Biology. Conducted by the Teaching Assistant Development Program. Graded Satisfactory (S) or No Credit (NC).