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2006-2007 General Catalog
University of California, Riverside Biomedical Sciences Subject abbreviation: BMSC
Craig V. Byus, Ph.D., Dean and Program Director Professors Professors Emeriti Associate Professors Lecturer
Clinical Professors
Associate Clinical Professors
Assistant Clinical Professors
UCR/UCLA Thomas Haider Program in Biomedical Sciences The mission of the prestigious UCR/UCLA Thomas Haider Program in Biomedical Sciences is to train physicians for distinguished medical careers in service to the people of California, with an emphasis on the needs of the underserved, inland, and rural populations. UCR provides a unique path of entrance to one of the country’s leading medical schools. Undergraduate students at UCR have exclusive access to 24 seats in medical school each year through the university’s joint program with the David Geffen School of Medicine at UCLA. UCR students admitted to the program complete years 1 and 2 of their medical education at UCR. They follow a state-of-the-art disease-based integrated curriculum taught by basic-science research faculty who work closely with a special cadre of highly qualified, community-based, physician faculty. This curriculum focuses on developing the process of life-long learning, employs problem-based learning, and requires extensive computer use. Years 3 and 4 of medical school are completed at UCLA, after which students receive their M.D. degrees from UCLA. Only undergraduates who entered UCR as freshmen or as transfer students may apply to the UCR/UCLA Program. Students must be enrolled at UCR for at least two years (six continuous full-time quarters) in the pursuit of a bachelor’s degree before entering the program. Only under exceptional circumstances will the program matriculate a student without a UCR baccalaureate degree. Applicants apply through the American Medical College Application Service, at www.amcas.org, following its guidelines and deadlines. Students may submit their applications at any time during the application period, as early as June (14 months before medical school classes begin in August at UCR) or as late as November 1 (9 months before classes begin). Applications without recent MCAT scores are considered incomplete. Review the application guidelines at www.biomed.ucr.edu and the application process at www.amcas.org. Unique aspects of the program include the following: • The 24 annual seats in the program are open to UCR undergraduate students and alumni only. • Students from any major may apply for one of the 24 seats as long as they will have completed the prerequisite course work and fulfilled other application requirements before entering the program. • Students accepted into the UCR/UCLA Program complete their first two years of medical school on the UCR campus and then move to UCLA to complete their medical education and graduate with an M.D. from UCLA. Prerequisite Courses Students preparing to apply to the UCR/UCLA Program should excel in their undergraduate academic program and complete specific course work before admission to the UCR/UCLA Program. Students who plan to transfer to UCR from another college or university for their undergraduate studies and then apply to the UCR/UCLA Program should complete, where possible, courses that have been designated as being equivalent to UCR courses. Transfer students from community colleges are encouraged to view the UCR/UCLA Program as an attractive and viable avenue to medical school. The UCR/UCLA Program prerequisite course curriculum is identical to the admissions requirements of the David Geffen School of Medicine at UCLA. Shown as UCR course work, it is as follows: English — one year of college English to include the study of English composition (ENGL 001A, ENGL 001B, ENGL 001C or equivalent) Physics — one year of college physics with laboratory (PHYS 002A, PHYS 02LA, PHYS 002B, PHYS 02LB, PHYS 002C, PHYS 02LC or equivalent) Chemistry — two years of college chemistry to include the study of inorganic chemistry and organic chemistry with laboratory (CHEM 001A, CHEM 001B, CHEM 001C, CHEM 01LA, CHEM 01LB, CHEM 01LC, and CHEM 112A, CHEM 112B, CHEM 112C or equivalent) Biology — one year of general biology with laboratory (BIOL 005A, BIOL 05LA, BIOL 005B, BIOL 005C or equivalent) Mathematics — one year of college mathematics to include introductory calculus and statistics (MATH 009A, MATH 009B and one course from STAT 100A, STAT 105, STAT 120A or equivalent) A one-quarter course in biochemistry to cover structure, function, and metabolism of biological molecules (BCH 100 or BCH 110A, BCH 110B or equivalent), while not required for admission, is highly recommended. Courses in Spanish language and the humanities are also highly recommended. AP results are not accepted as substitutes for the required science courses. Related Literature and References UCR currently has articulation agreements with most of the California community colleges. These agreements list specific community college courses that have been designated as comparable to UCR courses. See the statewide articulation Web site, at www.assist.org, or California community college Web sites. Academic Advising UCR undergraduates receive academic advising from professional staff and faculty of the department or program of their chosen major. Admission Students from any UCR major are eligible to apply for one of the 24 seats in the medical school each year. The admission requirements for the UCR/UCLA Program are identical to those for UCLA’s Geffen School of Medicine, but UCR students have a distinct advantage when applying to the UCR/UCLA Program. They compete only with other UCR students for those 24 seats in the program and the opportunity to earn an M.D. degree from UCLA’s Geffen School of Medicine. Admission considerations A strong candidate for admission to the UCR/UCLA Program has: • Completed the UCR/UCLA Program prerequisite course curriculum • An excellent undergraduate academic record • An excellent score on the Medical College Admission Test (MCAT) The strong candidate also shows a commitment to a career in medicine as demonstrated by volunteerism in medicine, clinical experience, or research. A solid record of community service is highly desired. It is important that applicants have made a difference to those around them. Examples of community service pursuits include volunteer work, leadership in campus organizations, mentor service for a peer or youth group, and commitment to and participation in religious or service organizations. Letters of Reference Applicants must submit letters from individuals such as professors and those who can speak about the applicant’s educational talents, character, work ethic, motivation, special traits, and positive influence on others. Admission Interview Qualified applicants will be invited to interview and have the opportunity to talk about themselves, their special qualities, and demonstrate their ability to interact with others. A Four-Year Medical Program Years 1 and 2 Students admitted to the UCR/UCLA Program are jointly enrolled at UCR and UCLA’s Geffen School of Medicine and take their first two years of medical school at UCR. Unlike other medical schools where students are taught in classes of 100 or more, the classes in the UCR/UCLA Program are small and comprised of 24 students during each of the first two years. This allows students to get to know their professors and receive the individual help and guidance they need to succeed. Classes in years 1 and 2 are taught by the UCR/UCLA Program faculty who are at the forefront of teaching and research and by community-based physician faculty with real-world understanding of medicine. Years 3 and 4 Students move to UCLA’s Geffen School of Medicine for the third and fourth years, where they participate in required and elective clinical rotations. UCLA Medical Center and the network of affiliated hospitals provide diverse settings for students to receive exemplary clinical experiences and utilize cutting-edge technology. In the fourth year, most graduating students are matched with one of their three top choices for a residency program. Students also have the opportunity to spend up to 12 weeks away at other universities to explore a particular area of interest. Externships in foreign countries exist as well. For more information UCR/UCLA Thomas Haider Program in Biomedical Sciences University Requirements See Undergraduate Studies section. College Requirements See College of Natural and Agricultural Sciences, Colleges and Programs section. B.S. Degree Requirements The following major requirements apply to students who matriculate into the Haider Program without a baccalaureate degree. These students are eligible to receive a B.S. degree in Biomedical Sciences upon satisfactory completion of the first year of the curriculum leading to the M.D. degree granted by the Geffen School of Medicine at UCLA. Major Requirements 1. Biological Sciences Core Curriculum (65-68 units) a) BIOL 005A, BIOL 05LA, BIOL 005B, BIOL 005C or equivalent b) CHEM 001A, CHEM 001B, CHEM 001C, CHEM 01LA, CHEM 01LB, CHEM 01LC, CHEM 112A, CHEM 112B, CHEM 112C or equivalent c) PHYS 002A, PHYS 002B, PHYS 002C, PHYS 02LA, PHYS 02LB, PHYS 02LC or equivalent d) MATH 008B or MATH 009A, MATH 009B or equivalent e) STAT 100A or equivalent f) BCH 100 or BCH 110A or equivalent 2. Courses taken during the first year of medical school (54 units) BMSC 211A, BMSC 212A, BMSC 213A, BMSC 214A BMSC 097. Research Tutorial in Biomedical Sciences (1-2) Laboratory, 3-6 hours. Prerequisite(s): grade point of 3.0 and consent of instructor. Laboratory tutorial in research related to biomedical sciences. To provide laboratory experience in the areas of physiology, microbiology, molecular biology, pharmacology, cell biology, immunology, biochemistry for exceptional lower-division students. A written report is required at the end of each quarter. Graded Satisfactory (S) or No Credit (NC). May be repeated for up to 6 units. Upper-Division Courses BMSC 194. Independent Reading (1-2) Discussion, 1 hour; outside research, 2-3 hours. Prerequisite(s): upper-division standing and consent of instructor and Divisional Dean. Independent study involving library projects on topics related to Biomedical Sciences. Independent study will be conducted under faculty supervision. A written report to be graded Satisfactory (S) or No Credit (NC) will be requested. Course is repeatable to a maximum of 4 units. BMSC 197L. Research for Undergraduates (1-3) Laboratory, 3-9 hours. Prerequisite(s): upper-division standing (completion of 90 quarter units) and consent of instructor. An introduction to the methods of research in biomedical sciences. The student will conduct investigation in an area of biomedical sciences under the supervision of a Division of Biomedical Sciences faculty member and submit a written report on his/her work. Course is repeatable. BMSC 202. Molecular Basis of Disease (3) S Lecture, 2 hours; discussion, 1 hour. Prerequisite(s): graduate standing or consent of instructor. Discussion of the molecular basis of disease with special emphasis on new developments and the broad application of approaches and techniques. Course is repeatable with consent of the student’s advisory committee; may be applied only once toward core requirements. BMSC 211A. Human Biology and Disease: Foundations (13) Lecture, 80 hours per quarter; discussion, 40 hours per quarter; laboratory, 34 hours per quarter. Prerequisite(s): first-year standing in medical school or consent of course coordinator. Covers basic principles of disease processes, genetics, and molecular, cellular, and developmental biology. Instruction is driven by cases and accomplished through lectures (maximum two hours/day) and discovery in small group discussions, laboratories, and conferences. Students using this course to fulfill the degree requirements for the B.S. degree in Biomedical Sciences receive a letter grade; other students receive a Satisfactory (S) or No Credit (NC) grade. Credit is awarded for only one of BMSC 211A or BMSC 223E. DeFea, Straus BMSC 211B. Human Biology and Disease: Foundations (14) Lecture, 78 hours per quarter; clinic, 52 hours per quarter; discussion, 40 hours per quarter; laboratory, 32 hours per quarter. Prerequisite(s): second-year standing in medical school; BMSC 214B. Advanced clinical perspective of the basic principles of disease processes, genetics, and molecular, cellular, and developmental biology. Instruction involves weekly cases and is presented through lectures (usually two hours/day) and discovery in small group discussions, laboratories, clinical skills development, and conferences. Graded Satisfactory (S) or No Credit (NC). Schiller BMSC 212A. Cardiovascular, Renal, and Respiratory Sciences (13) Lecture, 79 hours per quarter; discussion, 40 hours per quarter; laboratory, 61 hours per quarter. Prerequisite(s): first-year standing in medical school or consent of course coordinator. Covers anatomy, physiology, pathophysiology, physical diagnosis, and imaging in the cardiovascular, renal, and respiratory sciences. Instruction is driven by cases and accomplished through lectures (maximum two hours/day) and discovery in small group discussions, laboratories, and conferences. Students using this course to fulfill the degree requirements for the B.S. degree in Biomedical Sciences receive a letter grade; other students receive a Satisfactory (S) or No Credit (NC) grade. Credit is awarded for only one of BMSC 212A or BMSC 223F and for only one of BMSC 212A or BMSC 223G. Lytle, Quinton BMSC 212B. Cardiovascular, Renal, and Respiratory Sciences (12) Lecture, 62 hours per quarter; clinic, 33 hours per quarter; discussion, 44 hours per quarter; laboratory, 36 hours per quarter. Prerequisite(s): second-year standing in medical school; BMSC 213B. Advanced clinical perspective of anatomy, physiology, pathophysiology, physical diagnosis, and imaging in the cardiovascular, renal, and respiratory sciences. Instruction involves weekly cases and is presented through lectures (usually two hours/day) and discovery in small group discussions, laboratories, clinical skills development, and conferences. Graded Satisfactory (S) or No Credit (NC). Credit is awarded for only one of BMSC 212B or BMSC 223I. Shankel BMSC 213A. Gastrointestinal, Endocrine, and Reproductive Health (14) Lecture, 78 hours per quarter; discussion, 50 hours per quarter; laboratory, 48 hours per quarter; . Prerequisite(s): first-year standing in medical school or consent of course coordinator. Covers anatomy, biochemistry, pathophysiology, physical diagnosis, and imaging associated with gastrointestinal, endocrine, and reproductive health. Instruction is driven by cases and accomplished through lectures (maximum two hours/day) and discovery in small group discussions, laboratories, and conferences. Students using this course to fulfill the degree requirements for the B.S. degree in Biomedical Sciences receive a letter grade; other students receive a Satisfactory (S) or No Credit (NC) grade. Credit is awarded for only one of BMSC 213A or BMSC 223J. Shyy BMSC 213B. Gastrointestinal, Endocrine, and Reproductive Health (13) Lecture, 80 hours per quarter; clinic, 42 hours per quarter; discussion, 34 hours per quarter; laboratory, 18 hours per quarter. Prerequisite(s): second-year standing in medical school; BMSC 211B. Advanced clinical perspective of anatomy, biochemistry, pathophysicology, physical diagnosis, and imaging associated with gastrointestinal, endocrine, and reproductive health. Instruction involves weekly cases and is presented through lectures (usually two hours/day) and discovery in small group discussions, laboratories, clinical skills development, and conferences. Graded Satisfactory (S) or No Credit (NC). Carson, Walker BMSC 214A. Nervous and Musculoskeletal Systems (13) Lecture, 67 hours per quarter; discussion, 45 hours per quarter; laboratory, 58 hours per quarter. Prerequisite(s): first-year standing in medical school or consent of course coordinator. Covers anatomy, neurobiology, neurology, psychiatry, physical diagnosis, and imaging of the nervous and musculoskeletal systems. Instruction is driven by cases and accomplished through lectures (maximum two hours/day) and discovery in small group discussions, laboratories, and conferences. Colgan, D. Ethell BMSC 214B. Nervous and Musculoskeletal Systems (14) lecture, 73 hours per quarter; discussion, 49 hours per quarter; laboratory, 62 hours per quarter. Prerequisite(s): BMSC 214A. Covers anatomy, neurobiology, neurology, psychiatry, physical diagnosis, and imaging of the nervous and musculoskeletal systems. Instruction is driven by cases and accomplished through lectures (maximum two hours/day) and discovery in small group discussions, laboratories, and conferences. Ethell, Johnson BMSC 215. Integrative Human Biology and Disease (8) Discussion, 87 hours per quarter. Prerequisite(s): second-year standing in medical school; BMSC 212B. Reviews concepts of human biology and disease covered in BMSC 211A, BMSC 211B, BMSC 212A, BMSC 212B, BMSC 213A, BMSC 213B, BMSC 214A, BMSC 214B. Graded Satisfactory (S) or No Credit (NC). Shankel BMSC 222 (E-Z). Special Topics in Biomedical Sciences (2) Lecture, 1 hour; discussion, 1 hour. Prerequisite(s): graduate standing or consent of instructor. For BMSC 222V: BIOL 128/CBNS 128 or consent of instructor. Oral presentations and intensive small-group discussion of selected topics in the area of special competence of each faculty member. Course emphasizes recent advances in the special topic area and varies accordingly. E. Basic Epitheliology. Lytle, Quinton. G. Regulation of Gene Expression. Straus. J. Microbial Pathogenesis and Host-Pathogen Interactions. Schiller. L. Current Topics in Cell Biology. Walker. M. Hormone Action. Byus. N. Mechanisms of Steroid Hormones. Norman. O. Steroid Metabolism. Henry. P. Molecular Pharmacology. Johnson. Q. Mechanisms of Carcinogenesis. Byus. U. Transport Physiology. Lytle. V. Advanced Immunology. X. Mutagenesis and Genetic Instability. Grosovsky. Y. Cancer Genetics. Segments are repeatable. Byus in charge BMSC 223 (E-Z). Themes in Human Biology and Disease (2-4) For hours and prerequisites, see segment descriptions. Graduate students write a paper on current basic research relevant to the course theme. BMSC 223E. Inflammation, Autoimmunity, and Pathogen Defense (3) F Lecture, 23 hours per quarter; discussion, 8 hours per quarter; laboratory, 8 hours per quarter. Prerequisite(s): consent of course coordinator. Integrative view of the human immune system and inflammation in health and disease. Credit is awarded for only one of BMSC 211A or BMSC 223E. Carson BMSC 223F. Cardiovascular Physiology (4) F Lecture, 30.5 hours per quarter; discussion, 11.5 hours per quarter; laboratory, 5 hours per quarter. Prerequisite(s): consent of course coordinator. Integrative view of the human cardiovascular system in health and disease. Credit is awarded for only one of BMSC 212A or BMSC 223F. Lytle BMSC 223G. Renal Physiology (3) F Lecture, 22 hours per quarter; discussion, 8 hours per quarter; laboratory, 2 hours per quarter. Prerequisite(s): consent of course coordinator. Integrative view of human kidney function and dysfunction. Credit is awarded for only one of BMSC 212A or BMSC 223G. Quinton BMSC 223-I. Respiratory Physiology (3) F Lecture, 25 hours per quarter; discussion, 8 hours per quarter; laboratory, 6.5 hours per quarter. Prerequisite(s): consent of course coordinator. Integrative view of the human respiratory system in health and disease. Credit is awarded for only one of BMSC 212B or BMSC 223I. Quinton BMSC 223J. Gastrointestinal Physiology (3) W Lecture, 33 hours per quarter; laboratory, 6 hours per quarter. Prerequisite(s): consent of course coordinator. Integrative view of the human gastrointestinal system in health and disease. Credit is awarded for only one of BMSC 213A or BMSC 223J. Lytle BMSC 251. Colloquium in Biomedical Sciences (1) Colloquium, 1 hour. Prerequisite(s): graduate standing in Biomedical Sciences or consent of instructor. Specialized discussions by staff and students of current research topics in biomedical sciences. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 252. General Seminar in Biomedical Sciences (1) Seminar, 1 hour. Prerequisite(s): graduate standing. Oral presentations by staff and visiting scholars on current research topics in the field of biomedical sciences. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 254. Graduate Seminar in Biomedical Sciences (1) Seminar, 1 hour. Prerequisite(s): graduate standing. Oral reports by graduate students on current research topics in biomedical sciences. Students who present a seminar receive a letter grade; other students receive a Satisfactory (S) or No Credit (NC) grade. Course is repeatable. BMSC 290. Directed Studies (1-6) Outside research, 3-18 hours. Prerequisite(s): graduate standing in Biomedical Sciences or consent of instructor. Experimental or literature studies on specifically selected topics under direction of a staff member. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 297. Directed Research (1-6) Outside research, 3-18 hours. Prerequisite(s): graduate standing in Biomedical Sciences or consent of instructor. Directed research in biomedical sciences performed prior to advancement to candidacy in preparation for dissertation projects. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 299. Research for Dissertation (1-12) Outside research, 3-36 hours. Prerequisite(s): graduate standing in Biomedical Sciences or consent of instructor. Original research in the area selected for the advanced degree. Graded Satisfactory (S) or No Credit (NC). Course is repeatable. BMSC 302. Directed Teaching (2) Practicum, 6 hours. Prerequisite(s): graduate standing in Biomedical Sciences. Supervised teaching in medical school courses. Required for all Biomedical Sciences graduate students. Fulfills the teaching portion of the teaching requirement for the Ph.D.; four units are required for the Ph.D. Graded Satisfactory (S) or No Credit (NC). Course is repeatable to a maximum of 6 units.
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